📃 Paper Title: Age at surgery for undescended testis and risk of testicular cancer
🧍 Author: Pettersson
🕒 Year: 2007
📚 Journal: New England Journal of Medicine
🌎 Country: Sweden
ㅤContext to the study:
Can you tell me about a study that describes the risk of age at orchidopexy and testicular cancer?
ㅤ✅ Take-home message of study:
Treatment for undescended testis before puberty decreases the risk of testicular cancer.
Age at orchidopexy matters
Age <13y RR 2.2x (testes ca)
13 RR 5.4x
ㅤ Retrospective cohort
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Study participants:
16,983 men who underwent orchiopexy for undescended testis before age 20, in Sweden between 1964 and 1999.
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Key study outcomes:
56 cases of testicular cancer during follow-up. Age <13y RR 2.2x (testes ca). >13 RR 5.4x
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Study Limitations:
Could not assess the risk of cancer in the contralateral testis, or the effect of age at unilateral orchiopexy on the risk of cancer in the contralateral testis
(as information on laterality was not available in the registries used in the study)
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